Note: Hotel lists may include Sikeston motels and Sikeston bed & breakfast facilities as well.
| Photo | Hotel | Prices | Details |
|---|---|---|---|
![]() [larger] | Best Western Coach House Inn (220 South Interstate Drive) This all-suites hotel in Sikeston, Missouri offers charm, comfort and easy access to local attractions....[more] | $71-89 [update] | Info & Booking |
| Comfort Inn & Suites (109 Matthews Lane) Interstate location between Memphis and St. Louis in commercial area. One half mile from famous...[more] | $98-179 [update] | Info & Booking | |
| Country Hearth Inn Sikeston (100 Matthews Lane) Country Hearth Inn Offers Free Local Phone Calls, Hot Tub Suites With Microwave And Refrigerator,...[more] | $99 [update] | Info & Booking | |
![]() [larger] | Drury Inn Sikeston (2602 East Malone) Experience the excitement of Sikeston. Round up your friends and family for the annual Bootheel...[more] | $99-125 [update] | Info & Booking |
![]() [larger] | Holiday Inn Express Sikeston, Mo (120 S. Interstate) The Holiday Inn Express Sikeston Hotel is located at Mile Marker 67, off Interstate 55....[more] | $91-94 [update] | Info & Booking |
![]() [larger] | Pear Tree Inn Sikeston (2602 Rear East Malone) Enjoy a visit to Sikeston. Stay with Drury and experience Lamberts Cafe: Home of the...[more] | $49-83 [update] | Info & Booking |
![]() [larger] | Sikeston Days Inn (1330 South Main Street) Welcome to the Days Inn Sikeston. - Conveniently located on Highway 60 close to Interstates...[more] | $58-64 [update] | Info & Booking |
![]() [larger] | Super 8 Motel - Sikeston/Miner Area (2609 East Malone) Welcome to the Super 8 in Sikeston, Missouri! Convenient location off of Interstate 55 between...[more] | $55-80 [update] | Info & Booking |
Sikeston Streets With Multiple Hotels
Hotels On East Malone:
Hotels On Matthews Lane:
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