| Name | Styles | Significance | Periods |
|---|
Aaron Kinney House (Waller St.) | Federal | exploration, settlement | 1825-1849, 1850-1874, 1800-1824 |
All Saints Episcopal Church (4th and Court Sts.) | Gothic Revival | architecture | 1825-1849 |
Anderson Brothers Department Store (301-307 Chillicothe St.) | Renaissance | architecture | 1900-1924, 1925-1949, 1875-1899 |
Bigelow United Methodist Church (415 Washington St.) | Other | architecture | 1850-1874 |
Boneyfiddle Commercial Disrict (Roughly bounded by Front, Washington, 3rd and Scioto Sts.) | Federal, Greek Revival, Italianate | architecture, commerce, industry | 1825-1849, 1800-1824, 1900-1924, 1850-1874, 1875-1899 |
Cunningham - Maier House (506 Sixth) | Italianate | architecture | 1850-1874 |
Dole- Darrell House (322 Market St.) | Federal | architecture | 1825-1849 |
Elden House (634 Fourth St.) | Greek Revival, Italianate | architecture | 1850-1874 |
Eli Kinney House (317 Court St.) | Greek Revival | architecture, commerce | 1850-1874, 1825-1849 |
Evangelical Church of Christ (701 Fifth St.) | Other | architecture | 1875-1899 |
First Presbyterian Church (221 Court St.) | Greek Revival | architecture, religion | 1850-1874, 1825-1849 |
General U.S. Grant Bridge (Ohio R.-Chillicothe and Second St.) | Other | engineering, architecture, transportation | 1950-1974, 1925-1949, 1900-1924 |
George H. Gharky House (638 Fourth St.) | Greek Revival, Italianate | architecture | 1850-1874 |
Greenlawn Cemetery Chapel (Offnere St.) | Gothic | architecture | 1875-1899 |
Hurth Hotel (222 Chillicothe St.) | Other, Renaissance | architecture | 1925-1949 |
Joseph G. Reed Company (700 Second St.) | Romanesque | architecture | 1900-1924 |
Joseph Marsh House (701 Market St.) | Federal | architecture | 1800-1824, 1825-1849 |
Judge William V. Peck House (601 Market St) | Federal | architecture, law | 1825-1849, 1850-1874 |
Labold House and Gardens (633 Fourth St.) | Colonial Revival | architecture | 1925-1949, 1900-1924 |
Lyric Theater (820 Gallia St.) | No Style Listed | performing arts | 1900-1924 |
Meyer House (309 Washington St.) | Italianate | architecture | 1850-1874 |
Odd Fellows Hall (500--506 Court St.) | Italianate | architecture | 1850-1874 |
Portsmouth Fire Department No. 1 (642 Seventh St.) | Italianate | architecture | 1875-1899 |
Portsmouth Foundry and Machine Works (401 Third St.) | Italianate | architecture | 1850-1874 |
Purdum - Tracy House (626 Fourth St.) | Italianate, Greek Revival | architecture | 1850-1874, 1825-1849, 1875-1899 |
Scioto County Courthouse (Bounded by Seventh, Court, Sixth, & Washington Sts.) | Other, Late 19th And 20th Century Revivals | architecture | 1900-1924 |
Second Presbyterian Church (801 Waller St.) | Late Gothic Revival | architecture | 1925-1949, 1900-1924 |
Second Street Historic District (2nd St.) | Italianate, Queen Anne, Greek Revival | commerce, architecture | 1875-1899, 1900-1924, 1850-1874 |
Sixth Street Historic District (533, 534, 537, 538, 541, 542, 543, 547, & 548 Sixth St., W of Court St.) | Late Victorian, Greek Revival | architecture | 1900-1924, 1875-1899, 1850-1874 |
St. Mary's Roman Catholic Church (5th and Markets Sts) | Other | architecture | 1850-1874 |
Steindam House (725 Court St.) | Italianate | architecture | 1850-1874 |
Streich Apartments (716--722 Washington St.) | Other, Colonial | architecture | 1925-1949, 1900-1924 |
William Newman House (716 Second St.) | Other | architecture, politics, government, community planning and development | 1825-1849, 1850-1874 |
Zottman House (11 Offners St.) | Greek Revival | architecture | 1825-1849, 1900-1924, 1850-1874, 1875-1899, 1925-1949 |