| Name | Styles | Significance | Periods |
|---|
Boundary Street- Newberry Cotton Mills Historic District (Roughly bounded by Drayton, Boundary, Charles, Terrant and Crosson Sts.) | Classical Revival, Italianate | industry, architecture | 1900-1924, 1875-1899, 1850-1874 |
| Burton House | | architecture | 1850-1874 |
Caldwell Street Historic District (Caldwell St.) | Classical Revival | architecture | 1900-1924, 1875-1899 |
Coateswood (1700 Boundary St.) | | architecture, law, politics, government | 1825-1849 |
College Street Historic District (College St.) | Italianate, Bungalow, Craftsman | architecture | 1900-1924, 1875-1899 |
Cousins House (Nance St. Extension) | Second Empire | architecture | 1875-1899 |
Francis B. Higgins House (1520 Boundary St.) | Greek Revival, Federal | architecture | 1800-1824 |
George Mower House (1526 Boundary St.) | Queen Anne | architecture, politics, government | 1875-1899 |
Harrington Street Historic District (Harrington St.) | Classical Revival, Late Victorian | architecture | 1850-1874, 1875-1899, 1900-1924, 1925-1949 |
Ike Reighley House (2304 Main St.) | Stick, Eastlake | architecture | 1875-1899 |
Main Street Historic District (Roughly bounded by Harper, Summer, Douglas, Johnstone, Holman, and McMorris Sts.) | Greek Revival, Italianate, Classical Revival | architecture | 1925-1949, 1875-1899, 1825-1849, 1850-1874, 1900-1924 |
Newberry College Historic District (2100 College St.) | Classical Revival, Italianate | religion, architecture, education | 1875-1899, 1900-1924 |
Newberry Historic District (Bounded roughly by Friend, College, McKibben, and Harrington Sts.) | Romanesque | architecture, military | 1750-1799, 1875-1899, 1850-1874 |
Newberry Historic District (Boundary Increase) (Roughly bounded by Friend, McKibben, Harrington, Lindsay and Coates Sts.) | Renaissance, Classical Revival, Romanesque | architecture | 1900-1924, 1925-1949 |
Osborne Wells House (1101 Fair St.) | | architecture | 1850-1874 |
Stewart House (1001 Wilson St.) | Greek Revival | architecture | 1825-1849 |
Summer Brothers Stores (900 Main St.) | | architecture | 1875-1899 |
Timberhouse (1427 Ebenezer Rd.) | Greek Revival | architecture | 1850-1874 |
Vincent Street Historic District (Vincent and Crosson Sts.) | Late Victorian, Greek Revival | architecture | 1875-1899 |
Wells Japanese Garden (Lindsay St.) | | landscape architecture | 1925-1949 |
West Boundary Street Historic District (Boundary and Jessica Sts.) | Greek Revival | politics, government, architecture | 1925-1949, 1850-1874, 1825-1849 |